8% of all cases of craniosynostosis. The incidence of Crouzon syndrome is approximately 1 in 25,000 to 60,000 live births, accounting for 4. Abstract. 22q11. The aim of this qualitative investigation is to study the subjective experiences of transition from childhood to adulthood in individuals with Crouzon syndrome. Signs of Crouzon syndrome include: Craniosynostosis: When the sutures separating the bones of the skull fuse too soon. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Learn about Crouzon Syndrome, including symptoms, causes, and treatments. If you or a loved one is affected by this condition, visit NORD to find resources Crouzon syndrome (CS), first described in 1912 by the French neurosurgeon Octave Crouzon, is a rare genetic disorder caused by a mutation in the fibroblast growth factor receptor 2 ( FGFR2) gene. The Crossword Solver found 30 answers to "Jaw bone (8)", 8 letters crossword clue. Jaw Crossword Clue Answers. O. Click the answer to find similar crossword clues . • All forms of craniosynostosis are estimated to affect about 1 in 2,000-2,5000 live births. Mandibular growth has been reported to be normal in. Abstract. protruding lower jaw; overcrowded teeth; These facial abnormalities are a result of the following: Craniosynostosis: Premature (early) closure of growth plates of the skull that changes the shape. Common features include hypertelorism, exophthalmos and external strabismus, parrot-beaked nose, short upper lip, hypoplastic maxilla, and a relative mandibular prognathism (Reardon et al. The developer, so-called Hitpas released many. We have 3. The proptosis which can in turn put. 1. This can result in wide-set, bulging eyes. This early fusion prevents the skull from growing normally and affects the shape of the head and face. 7 Crouzon patients (4 females, 3 males). Cohen (1999) argued that this condition is separate from Crouzon syndrome for 2 main reasons: it is caused by a highly specific mutation of the FGFR3 gene, whereas multiple different. Apert syndrome treatments include: Eyedrops during the day, with. 14, 23 and 24 was done in the upper arch to provide space for alignment. Discussion. It was first described by the French neurosurgeon Dr. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Premature cranial suture closure results in growth inhibition perpendicular to. This process is called craniosynostosis. Crouzon syndrome is a genetic disorder characterized by premature fusion of the skull bones (craniosynostosis) and abnormal growth of the bones of the face, specifically the eye sockets and the midface. 13. Fish with an elongated jaw Crossword Clue. In children with a craniosynostosis syndrome, bones that fuse prematurely in the skull result in abnormal head shapes. Specifically, this syndrome affects the first branchial (or pharyngeal) arch, which is the precursor of the maxilla and mandible. You may want to know the content of nearby. History findings are described below. 4. History revealed that the parents noticed the developing protrusion of lower jaw when. Enter the length or pattern for better results. [ 6] Indeed, mutations in the FGFR2 gene have been detected in more than 50% of patients with Crouzon syndrome. The purpose of this study is to trace an operative algorithm with a long term follow up in a homogenous group of patients affected by Crouzon syndrome. Normally, the sutures in the human skull fuse after the. Individuals with Crouzon syndrome usually have normal intelligence. Here are the possible solutions for "Result" clue. Less commonly, there is a mutation of the FGFR3 gene which results in Crouzon syndrome syndrome with acanthosis nigricans. Described by a French neurosurgeon in 1912, it is a rare genetic disorder. Crouzon syndrome exhibits considerable phenotypic heterogeneity, in the aetiology of which genetics play an important role. rare in Crouzon syndrome. Similar to Apert Syndrome, Crouzon Syndrome results from mutations in the gene encoding FGFR-2, which has been mapped to chromosome 10q26. Lower Jaw Part. These two syndromes have several common features, including craniosynostosis, mid-facial deficiency, ocular proptosis, and hypertelorism. Clue Enter length and letters 2. Enter the length or pattern for better results. Severity of the syndrome varies from mild to severe among individuals. Crouzon syndrome is an inherited autosomal dominant disorder. The Crossword Solver found 30 answers to "lower jaw (4)", 4 letters crossword clue. Enter a Crossword Clue. 3 The prevalence rate of this syndrome is approximately 1 in 25,000 live births. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Fgfr2c C342Y/+ Crouzon syndrome mice show premature closure of the coronal suture and other craniofacial anomalies including malocclusion of teeth, most likely due to abnormal craniofacial form. 1,6,16. Apert, Crouzon and Pfeiffer syndrome) modern imaging has demonstrated multiple brain abnormalities which are mostly non-specific (e. 7% with Crouzon syndrome, 50. The Sun Coffee Time Crossword; Last Seen Dates. Crouzon a French neurologist first described the condition in an earlier part of the 20th century. Like so many other craniofacial conditions, Crouzon syndrome is highly variable across cases; some people are mildly affected, while others have a more severe presentation. Crouzon's syndrome (CS) is a rare autosomal dominant condition with multiple mutations of the fibroblast growth factor receptor (FGFR2) gene, which accounts for 4. In 1912, Crouzon described the hereditary syndrome of craniofacial dysostosis in a mother and son (Crouzon 1912 ). Premature fusion of the skull bones prevents the skull from growing normally and affects the shape of the child’s head and face. Craniosynostosis, or premature. Lower jaw Answer is: CHIN. 05 for height; p < 0. Pack Of Schemers Crossword Clue; The "S" Of 53 Down: Abbr Crossword Clue; Ratio (Tv Screen Metric) Crossword Clue; Playwright's Aphorism Enthralling Hearts Crossword Clue; Continuous Exercise Almost Causes Stroke Crossword Clue; Ascot, E. Crossword Clue. Click the answer to find similar crossword clues . Click the answer to find similar crossword clues. Crouzon syndrome is typically caused by heterozygous missense mutations in the third immunoglobulin domain of FGFR2. 05). Crossword Solver > Clues > Crossword-Clue: Jaw. We told the causes of crouzon syndrome then we will also tell you what’s the available treatment. We found 20 possible solutions for this clue. Crouzon Syndrome is characterised by a premature fusing of certain skull bones during the fourth week of development; specifically affecting the lower jaw bone and the palate. It is characterised by partial hearing loss, dry eyes, strabismus and underdevelopment of the upper jaw with facial deformities and malocclusion. Enter a Crossword Clue. The tongue often falls back in the throat, causing. A key feature of Crouzon is the premature closure of the skull bones, called craniosynostosis. This is usually performed during the teen years. Apert syndrome is named for the French physician who described the syndrome acrocephalosyndactylia in 1906. Enter a Crossword Clue. (a,b): A 4-month-old male infant with Crouzon syndrome showing bilateral proptosis, left exotropia,low set ears, bulging of the frontal and temporal bones, hypoplasia of superior maxilla,Results: The overall average distance from the pterygoid junction to the coronal plane in the patients with Crouzon syndrome was 21. Result Crossword Clue. Mayo Clinic notes this type of procedure is appropriate for children once their jaw growth stops, at about 14 to 16 years of age for females and 17 to 21 for males. Click the answer to find similar crossword clues . Sleep apnea or difficulty breathing. 1 Definition . All solutions for "jaw" 3 letters crossword answer - We have 5 clues, 79 answers & 115 synonyms from 3 to 18 letters. Last Seen Crosswords. Crouzon syndrome is an autosomal dominant condition. JAW, lower (60%) JAW part (60%) jaw muscle (60%) jaw bone (60%. Small ears. Crouzon syndrome is a genetic congenital condition characterized by skeletal and facial malformations. twist. This condition is also known as craniosysnostosis. Crouzon syndrome is one of the most common craniosynostosis facial syndromes caused by a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. This early fusion prevents the skull from growing normally and affects the shape of the head and face. The syndrome was first described in 1912 by French physician Octave Crouzon when he identified both a mother and daughter with what was originally called. (Crouzon's syndrome, n. Crouzon’s syndrome. There are around 200 known craniosynostosis syndromes. As a result of his report, this syndrome became known as maladie de Crouzon or, more often, as Crouzon 's disease or craniofacial dysostosis. Short forearms (missing radius bone) and short range of motion at the elbow. Telephone interviews were carried out with eight informants and data were analysed according to grounded theory. Research has identified the affected genes as the Fibroblast Growth Factor Receptor 2 (FGFR2) gene and FRGR3. Enter a Crossword Clue. Crouzon syndrome atau sindrom Crouzon adalah kelainan genetik yang ditandai dengan penggabungan dini tulang tengkorak tertentu ( craniosynostosis ). 4:1 has been reported. This syndrome has been associated with a variety of amino acid point mutations in the extracellular domain of fibroblast growth factor receptor 2. Core Tip: Crouzon syndrome (CS) is an autosomal dominant inherited craniofacial disorder caused by mutations in fibroblast growth factor receptor 2, but approximately 50% of cases result from de novo mutations. Crouzon syndrome, with a prevalence of 1:60,000 [], in most cases results from a mutation of the FGFR2 gene, which is either inherited in an autosomal dominant manner or arises as a de novo mutation, as in 30–60% of cases [2,3,4,5]. The signs and symptoms of Crouzon syndrome with acanthosis nigricans overlap with those of a similar condition called. You can either go back the Main Puzzle : Figgerits Special Rare Level 28 or discover the word of the next clue here : Crouzon syndrome results in lower jaw __. The Crossword Solver found 60 answers to "jaw", 7 letters crossword clue. Enter the length or pattern for better results. In a child with this syndrome, premature fusion of certain skull bones ( craniosynostosis) prevents the skull from growing normally and affects the shape of the head and face; sometimes causing. Between the ages of 4 and 6, she had surgery to correct the strabismus in her eyes, another surgery to remove her adenoids and tonsils, and multiple sleep studies. Click the answer to find similar crossword clues . The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Typically, the cranial vault presentation is a brachycephalic shape to the skull. Despite this, we are unaware of any previous study, besides case reports, that has assessed the dental. 6 people in every 100,000 and is caused by a genetic. Mast. org This condition is known as exophthalmos. Click the answer to find similar crossword clues . This early fusion prevents the skull from growing normally and affects the shape of the head and face. Crouzon syndrome is a rare genetic condition affecting primarily the skull and facial bones. Workup. Crouzon syndrome is an autosomal dominant condition primarily characterized by craniosynostosis. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Enter a Crossword Clue. And I have to say that Figgerits is a crossword reinvention. tip of lower jaw Crossword Clue. How Is Crouzon Syndrome. This can result in wide-set, bulging eyes. [1 2] It is one of the craniosynostosis syndrome that is caused by a mutation in the fibroblast growth factor receptor 2 gene. Crouzon's syndrome is caused by mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Genetic disorders like Down and Crouzon syndrome can cause Prognathism. shallow eye socket, which may lead to. It was last seen in The LA Times quick crossword. Crouzon, in 1912. Not the regular crosswords with the same graphics and gameplay, but a new way. complain. Visual acuity is reduced. They affect how certain cells in the body – including bone cells – grow. Crouzon syndrome is a rare genetic disorder that affects about 1 in 50,000 babies. The palate is often high and arched. Large, protruding lower jaw; Misalignment of teeth; High-arched, narrow palate, or cleft palate; Other symptoms and problems that can result from Crouzon syndrome are: Problems with development of the inner ear and hearing loss; Meniere disease—lightheadedness, vertigo, or ringing in the earsIn Crouzon syndrome, bones in the skull and face fuse too early, resulting in an abnormally shaped head, face, and teeth. In cases of craniofacial deformities, a specialist team will be needed for follow up and treatment. If certain letters are known already, you can provide them in the form of a pattern. Enter the length or pattern for better results. Many individuals with Crouzon syndrome require orthodontic treatment, often in combination with jaw surgery. The Fgfr2 W290R mouse has been characterized phenotypically and histologically and represents a model of human Crouzon syndrome. jutting part of lower jaw (4) Crossword Clue. It occurs due to mutation in fibroblast growth factor receptor II (FGFR-2) gene mapped on the chromosome loci 10q25-10q26. Affected individuals often have a prominent forehead (frontal bossing); a curved nose; unusually flat or underdeveloped mid-facial regions (midface hypoplasia); and a short upper lip. headdress. dangerous eye drying that can occur in Apert syndrome. Crouzon syndrome with acanthosis nigricans has an estimated prevalence of 1 per 1,000,000 newborns. Many features of Crouzon syndrome result from the premature fusion of the skull bones. The lack of hands and foot anomalies is crucial to distinguish Crouzon. A female-to-male sex ratio of 2. This produces prominent, staring eyes. Figgerits Answers and Cheats. Ophthalmologists should be aware of the many ophthalmic associations in Crouzon syndrome and must be alert toward conditions that may require early intervention. 3% in hair roots to 14. In a child with this syndrome, premature fusion of certain skull bones ( craniosynostosis) prevents the skull from growing normally and affects the shape of the head and face; sometimes causing. Crouzon Syndrome Definition. This syndrome affects around 5% of all the babies that have craniosynostosis. Crouzon syndrome (CS) is a rare genetic disorder characterized by premature closure of one or more cranial sutures and produces the characteristic craniofacial and other associated abnormalities. The Crossword Solver found 30 answers to "Fish with an elongated jaw", 3 letters crossword clue. Specifically, this syndrome affects the first branchial (or pharyngeal) arch, which is the precursor of the maxilla and mandible. This syndrome is due to a specific mutation in FGFR3 gene that can be identified by genetic testing. • It is the most common craniosynostosis syndrome. Early fusion of the skull bones prevents the skull from. Here we are today with the answers of the Game Figgerits. Find the latest crossword clues from New York Times Crosswords, LA Times Crosswords and many more. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Here the authors described a Crouzon syndrome case, which was asked for surgery treatment for the symptom of multisuture. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Please remember that I’ll always mention the master topic of the game : Figgerits Answers, the link to the previous level : Fine (syn. Apert syndrome is a rare autosomal dominant disorder characterized by craniosynostosis, craniofacial anomalies, and severe symmetrical syndactyly (cutaneous and bony fusion) of the hands and feet. For example, the disorder is typically associated with premature closure of the fibrous joints (cranial sutures) between. Result - crossword puzzle clues and possible answers. This study aims to conduct a comprehensive clinical and genetic investigation on a large family with members having various phenotypes, including acromesomelic dysplasia, type Maroteaux (AMDM), idiopathic short stature (ISS), Crouzon syndrome (CS). The results indicate that in Crouzon syndrome the craniofacial alterations depend not only on reduced synchondrosis activity of the anterior cranial base, but also of the posterior cranial base. The 14-yr-old boy had an abnormally shaped skull & face. The Crossword Solver found 30 answers to "lower jaw", 8 letters crossword clue. Airway Surgery for Crouzon Syndrome. Left untreated over a period of time, craniosynostosis could result in increased pressure on the developing brain (increased intracranial. Children with Crouzon syndrome may have one or more of these symptoms: Misshapen head: wide across the front and short from front to. Some of the symptoms of Crouzon Syndrome are. Enter the length or pattern for better results. Crouzon syndrome belongs to a large and heterogeneous group of conditions presenting with craniosynostosis, a common symptom of which is early fusion of one or more cranial sutures. Pronunciation of Crouzon syndrome with 2 audio pronunciations and more for Crouzon syndrome. d. Introduction. “Danner has always had horrible sleep apnea,” Sara explains. Sort A-Z. The Crossword Solver found 30 answers to "a bone of the lower jaw in mammals and other vertebrates (8)", 8 letters crossword clue. Crouzon syndrome is a genetically inherited syndrome characterized by craniosynostosis (premature fusion of coronal sutures) resulting in the skull and facial deformities. 1 Craniosynostosis is the premature fusion of the skull bones. Next step would be to visit the level’s master topic to find the answers of the other clues : Figgerits Rare Level 28. The clinical findings prompted a diagnosis of Crouzon syndrome. ,. Premature fusion of skull bones restricts skull. Enter the length or pattern for better results. Crouzon syndrome is a disorder characterized by early fusion of certain skull bones (craniosynostosis). Enter a Crossword Clue. Potential complications of Stickler syndrome include: Difficulty breathing or feeding. Downward slanting eyes (down-slanting palpebral fissures). 5 per 1,000,000 live births in United States. Enter a Crossword Clue. Symptoms. A small, underdeveloped upper jaw (hypoplastic maxilla) with protrusion of the lower jaw (relative mandibular prognathism) may also occur. Symptoms of this disorder may be: abnormalities of the skull, face and brain due to premature closure of the bones of the skull; swelling of the optic disk inside the eye; impaired vision; hearing loss; a beaked- shaped nose; an underdeveloped lower jaw; and/or a high arched palate. Cohen (1973) provided a review of all the. clevelandclinic. Apparently synonymous substitutions in FGFR2 affect splicing and result in mild. Deciduous canines and the left lateral incisor were present in the lower jaw, and the permanent canines, the left lateral incisor, and the lower right third molar were impacted. Crouzon syndrome makes up approximately 4. If I have a genetic condition that will result in the. Males and females are equally affected. Crossword answers are sorted by relevance and can be sorted by length as well. The Crossword Solver found 30 answers to "bird jaw (4)", 4 letters crossword clue. The proptosis which can in turn put. The acanthosis nigricans, which develops during childhood, is usually not apparent at presentation, so specific testing should be requested in the diagnostic workup of Crouzon syndrome. Enter a Crossword Clue. All synonyms & crossword answers with 3-11 Letters for JAW found in daily crossword puzzles: NY Times, Daily Celebrity, Telegraph, LA Times and more. This surgery involves cutting and repositioning the upper jaw to improve how the jaws and the teeth fit together. which results in hydrocephalus and venous dilation of the. 0. Figure 3. Van der Woude Syndrome This syndrome is caused by a mutation in the IRF6 gene and is a common inherited form of cleft lip and/or palate (opening in the lip and/or the roof of the mouth). They fuse together during adulthood when growth stops. , 2007; Padmanabhan, Hegde, & Rai, 2011). Crouzon syndrome is the most common type of craniofacial dysostosis anomaly which presents a great challenge for clinicians since birth. Enter the length or pattern for better results. Pierre Robin sequence (PRS) is a craniofacial disorder characterized in part by a small lower jaw and caused by a mutation in the regulatory gene. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Today's crossword puzzle clue is a quick one: Lower jaw. Click the answer to find similar crossword clues . Crouzon syndrome (OMIM: 123500) is caused by mutations in FGFR2, mapped to chromosome locus 10q26. Crouzon syndrome, also known as craniofacial dysostosis, is a complex genetic birth disorder that may affect a child’s face, skull, and teeth. There are other effects of this condition and ways to manage. It is the main cause of the prominent characteristics of CS, such as midfacial and. Abstract. Search for crossword clues found in the Daily Celebrity, NY Times, Daily Mirror, Telegraph and major publications. Crouzon syndrome is an autosomal dominant condition characterized by. Click the answer to find similar crossword clues . This case report illustrates a temporally coordinated therapy plan that succeeds in reducing the burden of care. Blindness can occur if retinal detachments aren't. Usually bilateral coronal sutures are involved, but multiple sutures may be affected. Crouzon's syndrome is an autosomal dominant disorder with complete penetrance and variable expressivity. Blindness. [2–4] About 30% to 60% of patients with Crouzon syndrome are sporadic. For instance, in the case of syndromic synostosis (e. Crouzon syndrome, also known as craniofacial dysostosis, is a complex genetic birth disorder that may affect a child’s face, skull, and teeth. Here the authors described a Crouzon syndrome case, which was asked for surgery treatment for the symptom of multisuture. FGFR2 mediates extracellular signals into cells and the mutations in the FGFR2 gene cause this syndrome occurrence. This means premature fusion of the fibrous joints (called. Crouzon syndrome is one of the most common craniosynostosis facial syndromes caused by a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Maxillary hypoplasia. Pierre Robin syndrome: A birth defect characterized by abnormalities in the facial bones, resulting in a smaller-than-normal lower jaw or receding chin. 8% of all craniosynostoses []. Many bones which form the skull are separated by sutures which allow the skull to expand and develop in synchrony with the growth of the. Enter a Crossword Clue. 1 Definition . Crouzon syndrome belongs to a large and heterogeneous group of conditions presenting with craniosynostosis, a common symptom of which is early fusion of one or more cranial sutures. Bulging, wide-set eyes. Enter the length or pattern for better results. Figgerits Crouzon syndrome results in lower jaw __: PROTRUSION. 2018 Mar 19. Crouzon syndrome. We found 20 possible solutions for this clue. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Crouzon, in 1912. Skull reshaping may need to be repeated as the child grows to give the best possible results. Click the answer to find similar crossword clues . 8 years. The manifestations of Crouzon syndrome result from the premature fusion of superior and posterior sutures of Symptoms of Crouzon Syndrome. The surgeon will use metal plates and screws to hold the jaw in its new position. This leads to the characteristic features of the condition, such as abnormal skull shape and acanthosis nigricans. Crouzon syndrome. Multiple synostoses in the sutures of the cranial base in this syndrome result in the hypoplasia of the midface, shallow orbits, a short nasal dorsum, maxillary hypoplasia, and, in severe cases,. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. A key feature of Crouzon is the premature closure of the skull bones, called craniosynostosis. The Crossword Solver found 30 answers to "Lower jaw bones", 9 letters crossword clue. Abstract. 4. Children with Van der Woude Syndrome have lower lip pits (mound of tissue with hole in center) and cleft lip, cleft palate or both. “Her airway was severely constricted, and her palate was soft and floppy. Ophthalmologists should be aware of the many ophthalmic associations in Crouzon syndrome and must be alert toward conditions that may require early intervention. If necessary, mid-facial advancement and jaw surgery can be done to provide adequate orbital. Crouzon syndrome is a genetic disorder characterized by the premature fusion of certain skull bones (craniosynostosis). Bone deformities in the middle of the face. C H I N. Crouzon syndrome is a genetic congenital condition characterized by skeletal and facial malformations. In affected members of the family an A-->G transition was found at position 886 in exon 5 of the fibroblast growth factor receptor 2 (FGFR2) gene. Small and poorly formed upper jaw and a protruding lower jaw; Hearing loss; Cleft lip (opening in the lip). The eye abnormalities include shallow orbits, hypertelorism, ocular proptosis, strabismus (squint) and, in extreme conditions, optical atrophy. Many features of Crouzon syndrome result from the premature fusion of the skull bones. In 1912, Crouzon described the hereditary syndrome of craniofacial dysostosis in a mother and son. Crouzon syndrome. How Is a Malocclusion of the Teeth Treated? The vast majority of malocclusion conditions will require no. The underdeveloped middle part of. 2. ) New mutation – 25 to 50% of cases (Head, 2010) Autosomal Dominant (Crouzon syndrome, 2010) 50% probability of transfer to offspring. Crouzon syndrome with acanthosis nigricans has an estimated prevalence of 1 per 1,000,000 newborns. Crouzon syndrome: (craniofacial dysostosis type 1 [CFD1]; Crouzon craniofacial dysostosis; Crouzon disease). Best corrected visual acuity was 5/10 for oculus dexter, count fingers at 2 m for oculus sinister with Snellen chart on ophthalmologic examination. Affected individuals often have a prominent forehead (frontal bossing); a curved nose; unusually flat or underdeveloped mid-facial regions (midface hypoplasia);. , 2005 ). Surgical. Search for crossword clues found in the Daily Celebrity, NY Times, Daily Mirror, Telegraph and major publications. Last Seen Crosswords. Introduction. It involves the premature fusion of sutures of the cranial vault. Multiple synostoses in the sutures of the cranial base in this syndrome result in the hypoplasia of the midface, shallow orbits, a short nasal dorsum, maxillary hypoplasia, and, in severe cases,. Its mutation will therefore cause a acceleration of the ossification process of all. Many features of Crouzon syndrome result from the premature fusion of the skull bones. Early fusion of sutures results in craniofacial. Mandible distraction starts with surgery to make a cut on both sides of the lower jaw. Levels of maternal somatic mosaicism for the mutation were estimated to range from 3. The most common features associated with Crouzon syndrome are: Tall, flattened forehead. Crossword Solver > Clues > Crossword-Clue: Jaw. Apert syndrome and Crouzon syndrome – These syndromes occur when skull bones fuse too soon while the baby is developing in the womb, affecting the appearance of the face. JAW, lower (60%) JAW part (60%) jaw muscle (60%) jaw bone (60%. concave profile with an asymmetric. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. It is the most common type of syndromic craniosynostosis. It is a letter guessing game where you have to find phrases. Upper jaw. shallow mid-face, which may lead to breathing difficulties. Lower jaw is a crossword puzzle clue that we have spotted 16 times. 75 for right eye, +5. Missing or malformed thumbs. Enter a Crossword Clue.